Zhou Q, Verne ML, Fields JZ, Lefante JJ, Basra S, Salameh H, Verne GN, Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome, Gut. 2018 Aug 14. pii: gutjnl-2017-315136. doi: 10.1136/gutjnl-2017-315136.
A randomized double-blinded, placebo-controlled study held during 8 weeks, had tested a treatment of consuming glutamine supplementation among patients of IBS and leaky gut after an infection.
The subjects were randomly divided: 4-5 subjects have received 5 gr of glutamine comparing to 52 subjects whom have received placebo.
The results of the study have shown that in IBS (irritable bowel syndrome) with an increased intestinal permeability (leaky gut) after an infection, glutamine supplementation does dramatically and safely decrease IBS symptoms.